Stanley Medical Research Institute (SMRI) and Brain Collection

The Stanley Medical Research Institute (SMRI) is a nonprofit organization supporting research on the causes of, and treatments for, schizophrenia and bipolar disorder. The Stanley Brain Collection is a widely used resource for researchers trying to find the causes of, and better treatments for, schizophrenia, bipolar disorder and major depression. Five cohorts are available for study; the Neuropathology Consortium, Array Collection, New Collection, Depression Collection and the Parietal Collection.

The SMRI is generating next generation sequencing data for multiple brain areas in the brain collections through international collaboration projects.

Currently available NGS data to download

• 1. The Neuropathology Consortium (15 each schizophrenia, bipolar disorder, depression and controls)
• • RNA-Seq data from prefrontal cortex
  • RNA-Seq data from orbitofrontal cortex
  • RNA-Seq data from hippocampus
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  2. The Array Collection (35 each schizophrenia, bipolar disorder and controls)
• • RNA-Seq data from cingulate cortex
  • RNA-Seq data from choroid plexus
  • RNA-Seq data from hippocampus
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  3. The Stanley New Collection (19 each schizophrenia, bipolar disorder and controls)
• • RNA-Seq data from choroid plexus
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  4. The Depression Collection (12 each depression with psychosis, depression without psychosis and controls)
• • RNA-Seq data from prefrontal cortex
  • RNA-Seq data from cingulate cortex
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  5. Combined Collections
• • RNA-Seq data from liver